The agency closed the bakery after an investigation revealed traces of cockroach infestation.
The cake, which is typically eaten on Jan. 6 to celebrate Three Kings Day, was distributed to stores around Orange County. It is unclear whether the infestation directly caused the illnesses.
Those who reported illnesses experienced multiple symptoms, including dizziness, numbness, stomach aches and palpitations.
Stores who have the Three Kings bread from Cholula’s are being asked to remove it from their shelves, and those who purchased the bread are being advised to discard it.