Seven people were arrested in relation to the second mass food poisoning incident in Ain al-Basha.
The owner of the restaurant and six of his employees were charged with four offences — causing harm, handling food in unsuitable conditions that made it harmful to human health, handling food that is not safe for human consumption and practicing a craft that causes harm.
The seven individuals will be detained for one week at Al-Balqa Reform and Rehabilitation Center (nice name — dp).
The death of a forty-year-old man, two days after the death of a child, after more than 800 people were exposed to food poisoning for eating contaminatedShawarma meals from a restaurant in the Al-Baqa’a area, northwest of Amman.
The official “Kingdom” television quoted the Minister of Health, Saad Jaber, as announcing the ministry’s registration, “a second death from the mass poisoning incident in al-Baq’a.”
The Ministry of Health announced in a statement last Wednesday that a 5-year-old child had died in hospital due to food poisoning.
“The laboratory tests … showed the presence of bacterial contamination in meat and chicken with the ‘Intercoxis Vials’ and’ Campylobacter” bacterium, “the ministry said.
And the official “Kingdom” television quoted the assistant secretary general for primary health care in the ministry, Adnan Ishaq, as saying that “the failure to cool poultry has spoiled the food and caused poisoning.”
Since the last case count update on July 9, 2020, the U.S. Centers for Disease Control reported 132 new laboratory-confirmed Cyclospora infections have been reported, including 16 from three new states: Georgia, Pennsylvania, and South Dakota.
As of July 22, 2020, a total of 641 people with laboratory-confirmed Cyclospora infections associated with this outbreak have been reported from 11 states: Georgia (1), Illinois (198), Iowa (195), Kansas (5), Minnesota (73), Missouri (57) Nebraska (55), North Dakota (6), Pennsylvania (2), South Dakota (13) and Wisconsin (36). The ill person from Georgia purchased and ate a bagged salad product while traveling in Missouri.
Illnesses started on dates ranging from May 11, 2020 to July 5, 2020. Ill people range in age from 10 to 92 years with a median age of 59 and 52% are female. Of 636 people with available information, 37 people (6%) have been hospitalized. No deaths have been reported.
Illnesses might not yet be reported due to the time it takes between when a person becomes ill and when the illness is reported. This takes an average of 4 to 6 weeks. If the number of cases reported by CDC is different from the number reported by state or local health officials, data reported by local jurisdictions should be considered the most up to date. Any differences may be due to the timing of reporting and website updates.
This investigation is ongoing.
The CDC says that it is specifically examining salad ingredients (iceberg lettuce, carrots, red cabbage) for the purposes of its investigation. The affected products include salad mixes made by Fresh Express, Hy-Vee Inc., Little Salad Bar, Signature Farms, Marketside and Hy-Vee. The products were sold at ALDI, Giant Eagle, Hy-Vee, Jewel-Osco, ShopRite, and Walmart locations.
The products were manufactured in Streamwood, Illinois at a Fresh Express production facility.
“Cyclosporiasis is an intestinal infection caused by the Cyclospora parasite,” the CDC says. “A person may become infected after ingesting contaminated food or water. Common symptoms include severe abdominal pain, diarrhea, nausea and vomiting, body aches and fatigue. The infection is treated with antibiotics and most people respond quickly to treatment.”
Specifically, the CDC says the products with a Z178 code or lower and “Best by” date that runs through July 14, 2020 are the ones potentially affected by the contamination.
However, only Georgia, Illinois, Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, Pennsylvania, South Dakota and Wisconsin have reported cases of Cyclospora related to eating the salad mix. According to the CDC, the dates of the illness range from May 11, 2020 to July 5, 2020, with 37 people hospitalized as of Friday. Patients are ages 10 to 92 years with a median age of 59 years as of Friday’s data. No related deaths have been reported. People can go 4 to 6 weeks before noticing any symptoms of Cyclospora, the CDC says.
Write down what you ate in the two weeks before you started to get sick.
Report your illness to the health department.
Assist public health investigators by answering questions about your illness.
On June 27, 2020, Fresh Express Fresh Express brand and private label brand salad products produced at its Streamwood, IL facility that contain iceberg lettuce, red cabbage, and/or carrots due to possible Cyclospora contamination.
The Public Health Agency of Canada is investigating an outbreak of Cyclospora infections occurring in three Canadian provinces. Exposure to certain Fresh Express brand salad products containing iceberg lettuce, carrots, and red cabbage, has been identified as a likely source of the outbreak.
Epidemiologic and traceback evidence indicates that bagged salad mix containing iceberg lettuce, carrots, and red cabbage produced by Fresh Express is a likely source of this outbreak.
CDC and FDA continue to investigate to determine which ingredient or ingredients in the salad mix was contaminated and whether other products are a source of illnesses.
CDC will provide updates when more information is available.
Human Parasitic Diseases: A Diagnostic Atlas is a comprehensive and invaluable resource for parasitologists, microbiologists, pathologists, and infectious disease practitioners. Lawrence R. Ash, PhD, and Thomas C. Orihel, PhD, have curated a beautiful photographic series of common and rare parasites shown in tissue, blood, feces, and free-living forms. Organized by phylum, genera, and species, this book provides detailed yet practical assistance in identifying and diagnosing human parasitic diseases. Each section starts with a brief overview of the epidemiology, life cycle, transmission, and clinical manifestations of the parasite, detailed enough to orient the reader to the clinical relevance of the pathogen without distracting from its macroscopic and microscopic diagnostic features. The authors provide up-to-date references of each parasite’s clinical manifestations and diagnostic procedures.
In addition to the beautiful, high-quality photomicrographs, the authors supplement the book with detailed diagrams clarifying the key microscopic diagnostic features. These details enable the reader to differentiate between closely related parasites.
This book offers many unique aspects. First, the authors provide multiple images comparing subtle differences in the appearance of the same parasite, which will reassure anyone who has struggled to identify a blood smear of a parasite that does not quite fit the textbook example. These images emphasize the subtlety of microscopic identification and pattern recognition. Second, this atlas emphasizes the appearance of parasites in histologic findings and tissue. The authors acknowledge the difficulty of making a histologic diagnosis on the basis of fragments of larger parasites or those that have degenerated in tissues. Third, the book contains a 1911 Arthur Looss quote emphasizing the interconnectedness of animal and human parasites and highlighting the need to consider animal pathogens that have rarely infected humans. This perspective is relevant in a world with increasingly immunosuppressed patients and unprecedented levels of travel and global trade. Therefore, this book is a compelling reference volume for pathologists and microbiology or clinical infectious disease training programs.
Particularly useful for today’s clinical infectious diseases practitioners is the last section of the book, which covers artifacts for which macroscopic or microscopic appearance could be easily confused even by an experienced pathologist. This section is a helpful reminder of the diagnostic challenges facing clinicians seeing patients who believe they have an infestation but in whom no parasite can be found.
I will certainly use this atlas as a reference and training guide and will most likely browse through its pages before recertification examinations. Any reader with an inclination towards parasitology will appreciate the authors and their colleagues’ fascinating careers in this field.
Human Parasitic Diseases: A diagnostic atlas, August 2020
I’m still troubled the world lost such a gifted and incisive songwriter as John Prine to coronavirus.
And I’m lonely, because I live downstairs.
Social distancing and “stay-at-home” orders are essential to contain the coronavirus outbreak (COVID-19), but there is concern that these measures will increase feelings of loneliness, particularly in vulnerable groups. The present study examined change in loneliness in response to the social restriction measures taken to control the coronavirus spread.
A nationwide sample of American adults (N 1,545; 45% women; ages 18 to 98, M 53.68, SD 15.63) was assessed on three occasions: in late January/early February 2020 (before the outbreak), in late March (during the President’s initial “15 Days to Slow the Spread” campaign), and in late April (during the “stay-at-home” policies of most states). Contrary to expectations, there were no significant mean-level changes in loneliness across the three assessments (d .04, p .05). In fact, respondents perceived increased support from others over the follow-up period (d .19, p .01). Older adults reported less loneliness overall compared to younger age groups but had an increase in loneliness during the acute phase of the outbreak (d .14, p.05). Their loneliness, however, leveled off after the issuance of stay
Trajectory of loneliness in response to COVID-19, 2020
American Psychological Association
Martina Luchetti, Ji Hyun Lee, Damaris Aschwanden, Amanda Sesker, Jason E. Strickhouser, Antonio Terracciano, and Angelina R. Sutin
Rachel Gross of the New York Times writes, the first sign is the smell: smoky, like a campfire, with a hint of urine. The second is the koala’s rear end: If it is damp and inflamed, with streaks of brown, you know the animal is in trouble. Jo, lying curled and unconscious on the examination table, had both.
Jo is a wild koala under the purview of Endeavour Veterinary Ecology, a wildlife consulting company that specializes in bringing sick koala populations back from the brink of disease. Vets noticed on their last two field visits that she was sporting “a suspect bum,” as the veterinarian Pip McKay put it. So they brought her and her 1-year-old joey into the main veterinary clinic, which sits in a remote forest clearing in Toorbul, north of Brisbane, for a full health check.
Ms. McKay already had an inkling of what the trouble might be. “Looking at her, she probably has chlamydia,” she said.
Humans don’t have a monopoly on sexually transmitted infections. Oysters get herpes, rabbits get syphilis, dolphins get genital warts. But chlamydia — a pared-down, single-celled bacterium that acts like a virus — has been especially successful, infecting everything from frogs to fish to parakeets. You might say chlamydia connects us all.
This shared susceptibility has led some scientists to argue that studying, and saving, koalas may be the key to developing a long-lasting cure for humans. “They’re out there, they’ve got chlamydia, and we can give them a vaccine, we can observe what the vaccine does under real conditions,” said Peter Timms, a microbiologist at the University of Sunshine Coast in Queensland. He has spent the past decade developing a chlamydia vaccine for koalas, and is now conducting trials on wild koalas, in the hopes that his formula will soon be ready for wider release. “We can do something in koalas you could never do in humans,” Dr. Timms said.
In koalas, chlamydia’s ravages are extreme, leading to severe inflammation, massive cysts and scarring of the reproductive tract. In the worst cases, animals are left yelping in pain when they urinate, and they develop the telltale smell. But the bacteria responsible is still remarkably similar to the human one, thanks to chlamydia’s tiny, highly conserved genome: It has just 900 active genes, far fewer than most infectious bacteria.
Toxoplasma gondii is an intracellular parasite that reconfigures its host cell to promote pathogenesis. One consequence of Toxoplasma parasitism is increased migratory activity of host cells, which facilitates dissemination.
Here, we show that Toxoplasma triggers the unfolded protein response (UPR) in host cells through calcium release from the endoplasmic reticulum (ER). We further identify a novel role for the host ER stress sensor protein IRE1 in Toxoplasma pathogenesis. Upon infection, Toxoplasma activates IRE1, engaging its noncanonical role in actin remodeling through the binding of filamin A. By inducing cytoskeletal remodeling via IRE1 oligomerization in host cells, Toxoplasma enhances host cell migration in vitro and dissemination of the parasite to host organs in vivo.
Our study has identified novel mechanisms used by Toxoplasma to induce dissemination of infected cells, providing new insights into strategies for treatment of toxoplasmosis.
Toxoplasma gondii co-opts the unfolded protein response to enhance migration and dissemination of infected host cells, 7 July 2020
American Society for Microbiology
Leonardo Augusto, Jennifer Martynowicz, Parth H. Amin, Nada S. Alakhras, Mark H. Kaplan, Ronald C. Wek, William J. Sullivan Jr.
Outbreak News Today reports that Russian officials report last week that 10 people from Altai Republic, near the Mongolian border, were hospitalized with trichinosis after consuming undercooked bear cub.
The regional office of Rospotrebnadzor said, “Not all bears, of course, are infected wi. But this sometimes happens, there were simply no such massive cases. We are in control of the situation.”
Earlier, Russians were advised to avoid contact with raw meat and animal blood in Altai, so as not to get infected with bubonic plague. As the infectious disease doctor Ivan Konovalov stated , outbreaks of the plague periodically occur in Russia, where the traditions of local peoples include eating raw animal meat. He emphasized that there is a vaccine against the plague pathogen.
Trichinosis is a parasitic disease caused most commonly by the roundworm Trichinella spiralis. If someone ingests undercooked or raw meat with the encysted larvae, the stomach acid releases the larvae which mature to adults in the intestine.
After about a week the female starts releasing larvae which enter the bloodstream and find their way to skeletal muscle where they encapsulate.
There can be gastrointestinal symptoms mimicking acute food poisoning when there is activity of the adults in the intestine.
As the co-author of Mad Cows and Mother’s Milk (1997) I couldn’t let this slide.
A lab accident in 2010 likely led to a woman’s untimely death nearly a decade later, according to doctors in France. In a recent case study, they describe how a woman in her early 30s developed a universally fatal brain disorder years after she had pierced her skin with equipment used to handle infectious rogue proteins called prions.
Prions are a type of protein that exist naturally in our brains. Ordinarily, they’re thought to be harmless, though their exact function remains a mystery. But rarely, they can transform into a misfolded version that compels normal prions to change shape, too. Over years or even decades, this cascade of misfolded prions destroys the brain from the inside out, leaving behind signature sponge-like holes under a microscope. Because of these holes, prion diseases are also medically known as transmissible spongiform encephalopathies.
Prion diseases often happen with no clear rhyme or reason — native prions just seem to spontaneously pull a heel turn. Other times, a person’s inherited genetics are to blame. But what makes prions even scarier is that they can be also infectious, spreading from one person to another or across different species of animals.
In the 1980s and 1990s, scientists noticed outbreaks of cows that were developing their own prion disease, which became popularly known as mad cow disease. Years later, we began seeing people develop a never-before-seen sort of prion disease, which was eventually traced to them eating contaminated beef (meanwhile, the cows were being infected from eating animal feed that contained brain matter from other infected cows and possibly sheep). Medically, this infectious type of prion disease became known as variant-Creutzfeldt-Jakob disease (vCJD), to distinguish it from the classic version that’s the most common but still very rare prion disease in humans.
The young woman had been a lab technician in a research facility studying prions in 2010, according to a case study published in the New England Journal of Medicine this month. One day in May, she was using a pair of curved forceps to handle frozen, prion-infected brain samples taken from mice genetically engineered to develop human prions, when the forceps slipped and stabbed into her thumb. Though she was wearing two pairs of protective gloves, the sharp ends pierced her skin and drew blood. She was only 24 at the time.
About seven and a half years later, in November 2017, she began experiencing a burning pain down her right shoulder and neck. Her condition worsened over the next year, to the point of memory impairment, visual hallucinations, and muscle stiffness along her right side by January 2019. Eventually, 19 months after the onset of symptoms, she died. Tests before her death strongly suggested she had vCJD, which was confirmed post-mortem.
It’s possible that the woman might have caught vCJD through eating tainted beef made before sharp shifts in the meat processing industry came along that seemed to end the threat of mad cow disease in the 1990s. But that would be very unlikely, according to the authors, because vCJD isn’t thought to take longer than a decade to show up after exposure in people with the woman’s genetic makeup. Nearly all known cases of vCJD have been in people who share a specific but relatively common genetic variation of their prion gene, called MM, which the women also carried. But the timing does work out if you assume she caught vCJD through the lab accident.
Prion diseases remain incredibly rare, and even in cases where they are infectious, genetics seem to strongly influence the risk of actually becoming sick (only a few hundred cases of vCJD have ever been reported worldwide). But this isn’t the first time that a case of vCJD has been linked to exposure in a lab, according to the authors, suggesting that more could be done to keep scientists and technicians safe during the valuable work they do to understand these utterly mysterious things. Prions are notoriously very hard to “kill” using traditional decontamination methods, which provides an added source of concern for medical procedures involving the brain.
“This is an unexpected medical event and of course unexpected timing. However the doctor’s advice on having surgery needs to be followed,” Peters, who is also the foreign minister, said in a statement.